| Date | Home Team | | vs. | | Away Team | Face Off | Competition |
| Saturday, 4 September 2021 | Bees |  | vs. |  | Raiders | 17:15 | Pre-Season |
| Sunday, 5 September 2021 | Raiders | | vs. | | Bees | 17:15 | Pre-Season |
| Saturday, 11 September 2021 | Swindon Wildcats |  | vs. | | Bees | 18:15 | Pre-Season |
| Sunday, 12 September 2021 | Bees | | vs. | | Swindon Wildcats | 17:00 | Pre-Season |
| Saturday, 18 September 2021 | Leeds Knights |  | vs. | | Bees | TBC | Cup |
| Sunday, 19 September 2021 | Bees | | vs. | | Swindon Wildcats | 17:00 | Cup |
| Saturday, 25 September 2021 | Peterborough Phantoms |  | vs. | | Bees | 19:00 | Cup |
| Sunday, 26 September 2021 | Bees | | vs. |  | Sheffield Steeldogs | 17:00 | Cup |
| Saturday, 2 October 2021 | Raiders | | vs. | | Bees | 17:15 | Cup |
| Sunday, 3 October 2021 | Bees | | vs. |  | Milton Keynes Lightning | 17:00 | Cup |
| Saturday, 9 October 2021 | Telford Tigers |  | vs. | | Bees | 19:00 | Cup |
| Sunday, 10 October 2021 | Bees | | vs. |  | Basingstoke Bison | 17:00 | Cup |
| Saturday, 16 October 2021 | Leeds Knights | | vs. | | Bees | TBC | League |
| Sunday, 17 October 2021 | Bees | | vs. | | Milton Keynes Lightning | 17:00 | League |
| Saturday, 23 October 2021 | Sheffield Steeldogs | | vs. | | Bees | 19:30 | League |
| Sunday, 24 October 2021 | Bees | | vs. | | Sheffield Steeldogs | 17:00 | League |
| Friday, 29 October 2021 | Raiders | | vs. | | Bees | 19:00 | League |
| Sunday, 31 October 2021 | Bees | | vs. | | Leeds Knights | 17:00 | League |
| Saturday, 6 November 2021 | Basingstoke Bison | | vs. | | Bees | 18:30 | League |
| Sunday, 7 November 2021 | Bees | | vs. | | Swindon Wildcats | 17:00 | League |
| Saturday, 13 November 2021 | Milton Keynes Lightning | | vs. | | Bees | 19:00 | League |
| Sunday, 14 November 2021 | Bees | | vs. | | Milton Keynes Lightning | 17:00 | League |
| Saturday, 20 November 2021 | Leeds Knights | | vs. | | Bees | TBC | League |
| Sunday, 21 November 2021 | Bees | | vs. | | Swindon Wildcats | 17:00 | League |
| Saturday, 27 November 2021 | Bees | | vs. | | Telford Tigers | 17:15 | League |
| Sunday, 28 November 2021 | Telford Tigers | | vs. | | Bees | 18:00 | League |
| Sunday, 5 December 2021 | Bees | | vs. | | Leeds Knights | 17:00 | League |
| Saturday, 11 December 2021 | Swindon Wildcats | | vs. | | Bees | 18:15 | League |
| Sunday, 12 December 2021 | Bees | | vs. | | Peterborough Phantoms | 17:00 | League |
| Saturday, 18 December 2021 | Bees | | vs. | | Telford Tigers | 17:15 | League |
| Sunday, 19 December 2021 | Peterborough Phantoms | | vs. | | Bees | 17:30 | League |
| Monday, 27 December 2021 | Bees | | vs. | | Raiders | TBC | League |
| Tuesday, 28 December 2021 | Raiders | | vs. | | Bees | 19:00 | League |
| Saturday, 1 January 2022 | Swindon Wildcats | | vs. | | Bees | 18:15 | League |
| Sunday, 2 January 2022 | Bees | | vs. | | Basingstoke Bison | 17:00 | League |
| Saturday, 8 January 2022 | Bees | | vs. | | Telford Tigers | 17:15 | League |
| Sunday, 9 January 2022 | Telford Tigers | | vs. | | Bees | 18:00 | League |
| Saturday, 15 January 2022 | Peterborough Phantoms | | vs. | | Bees | 19:00 | League |
| Saturday, 22 January 2022 | Basingstoke Bison | | vs. | | Bees | 18:30 | League |
| Sunday, 23 January 2022 | Bees | | vs. | | Raiders | 17:00 | League |
| Saturday, 29 January 2022 | Bees | | vs. | | Peterborough Phantoms | 17:15 | League |
| Sunday, 30 January 2022 | Sheffield Steeldogs | | vs. | | Bees | 16:30 | League |
| Saturday, 5 February 2022 | Bees | | vs. | | Sheffield Steeldogs | 17:15 | League |
| Sunday, 6 February 2022 | Raiders | | vs. | | Bees | 17:15 | League |
| Saturday, 12 February 2022 | Milton Keynes Lightning | | vs. | | Bees | 19:00 | League |
| Sunday, 13 February 2022 | Bees | | vs. | | Basingstoke Bison | 17:00 | League |
| Saturday, 19 February 2022 | Bees | | vs. | | Peterborough Phantoms | 17:15 | League |
| Friday, 25 February 2022 | Bees | | vs. | | Raiders | 19:45 | League |
| Saturday, 26 February 2022 | Basingstoke Bison | | vs. | | Bees | 18:30 | League |
| Sunday, 27 February 2022 | Telford Tigers | | vs. | | Bees | 18:00 | League |
| Saturday, 5 March 2022 | Peterborough Phantoms | | vs. | | Bees | 19:00 | League |
| Sunday, 6 March 2022 | Bees | | vs. | | Milton Keynes Lightning | 17:00 | League |
| Saturday, 12 March 2022 | Swindon Wildcats | | vs. | | Bees | 18:15 | League |
| Sunday, 13 March 2022 | Bees | | vs. | | Sheffield Steeldogs | 17:00 | League |
| Saturday, 19 March 2022 | Leeds Knights | | vs. | | Bees | TBC | League |
| Sunday, 20 March 2022 | Bees | | vs. | | Swindon Wildcats | 17:00 | League |
| Saturday, 26 March 2022 | Sheffield Steeldogs | | vs. | | Bees | 19:30 | League |
| Sunday, 27 March 2022 | Bees | | vs. | | Leeds Knights | 17:00 | League |
| Saturday, 2 April 2022 | Milton Keynes Lightning | | vs. | | Bees | 19:00 | |
| Sunday, 3 April 2022 | Bees | | vs. | | Basingstoke Bison | 17:00 | |
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